General features and properties of insertion sequence elements

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Acknowledgements and Sources

Except where otherwise cited, the major part of the information included on this site is based on the following articles:

  • - Mahillon, J. , Chandler, M. (1998). Insertion Sequences. Microbiol. Mol. Biol. Revs. 62 : 725-774.
  • - Siguier, P.,  Gourbeyre, E, Chandler, M. (2014). Bacterial insertion sequences: their genomic impact and diversity. FEMS Microbiol Rev 1–28 DOI: 10.1111/1574-6976.12067
  • - He, S., Corneloup A., Guynet C., Lavatine L., Caumont-Sarcos A., Siguier P., Marty B., Dyda F., Chandler M., Ton Hoang, B..(2015) The IS200/IS605 Family and “Peel and Paste” Single-strand Transposition Mechanism.  Microbiol Spectrum 3(4):MDNA3-0039-2014. doi:10.1128/microbiolspec. MDNA3-0039-2014.
  • - Chandler, M., Fayet O., Rousseau P., Ton Hoang B., Duval-Valentin G. (2015) Copy Out – Paste in Transposition of IS911  Microbiol Spectrum 3(4) : MDNA3- 0031-2014. doi:10.1128/microbiolspec. MDNA3-0031-2014.
  • - Siguier, P., Gourbeyre, E., Varani ,A M., Ton-Hoang, B., Chandler, M. (2015). Everyman’s Guide to Bacterial Insertion Sequences Microbiol Spectrum 3(2):MDNA3-0030-2014. doi:10.1128/microbiolspec.MDNA3-0030-2014. (Mobile DNA III)
  • - Chandler, M., de la Cruz, F., Dyda, F., Hickman, A., Moncalian, G. and Ton-Hoang, B. (2013) Breaking and joining single-stranded DNA: the HUH endonuclease superfamily. Nat. Rev. Microbiol. doi:10.1038/nrmicro3067
  • - Siguier P, Perochon J, Lestrade L, Mahillon J, Chandler M. (2006) ISfinder: the reference centre for bacterial insertion sequences. Nucleic Acids Res. 34(Database issue):D32-6.

We would also like to thank O. Barabas, A. Hickman and F. Dyda for providing the animated structural models.

We also acknowledge the contributions of other members of the ex-Chandler lab: A. Achard, M. Betermier, A. Caumont-Sarcos, A. Corneloup, G. Duval-Valentin, JM. Escoubas, P. Gamas, E. Guegen , C. Guynet, L. Haren,  S.He, L. Lavatine, C. Loot, B. Marty, C. Normand, P. Rousseau, P. Polard, N. Pouget, B. Ton Hoang, C. Turlan, AM. Varani, D. Zerbib. 

You could found all information about IS and transposon on the dedicaced Wiki : TnPedia.