The third transposase
family is represented by IS607 which
carries a Tpase closely related to serine recombinases such as the resolvases
of Tn3 family elements. Little is
known about their transposition mechanism. However, it appears likely, in view
of the known activities of resolvases (Grindley,
2002), that IS607 transposition may involve a double strand DNA intermediate (Grindley cited as
pers. comm. in (Filee, et al., 2007)) see also (Boocock
& Rice, 2013) (Fig 1.7.1).
MR & Rice PA (2013) A proposed mechanism for IS607-family serine
transposases. Mob DNA 4: 24.
J, Siguier P & Chandler M (2007) Insertion sequence diversity in archaea. Microbiol Mol Biol Rev 71: 121-157.
- Grindley NDF (2002) The movement of
Tn3-like elements: transposition and cointegrate resolution. Mobile DNA II,(Craig NL, Craigie R,
Gellert M & Lambowitz A, ed.^eds.), p.^pp. 230-271. ASM press, Washington